Tagged: Sleep Review

Apolipoprotein Levels, Insulin Resistance Influence Obstructive Sleep Apnea 0

Apolipoprotein Levels, Insulin Resistance Influence Obstructive Sleep Apnea

In a cohort of adults assessed for sleep issues, those in the highest quartile of apolipoprotein B to apolipoprotein A-I ratio were at the greatest risk for obstructive sleep apnea and insulin resistance, according to findings published in Nutrition, Metabolism & Cardiovascular Diseases.

“The ApoB/ApoA-I ratio is positively associated with the risk of prediabetes, diabetes, metabolic syndrome, nonalcoholic fatty liver disease and CVD,” Jian Guan MD, PhD, of the department of otorhinolaryngology-head and neck surgery at Shanghai Jiao Tong University Affiliated Sixth People’s Hospital in Shanghai, and colleagues wrote.

“Considering that [obstructive sleep apnea] may promote dyslipidemia, we hypothesized a positive association between severity of [obstructive sleep apnea] and the ApoB/ApoA-I.”

from Sleep Review http://www.sleepreviewmag.com/2019/08/apolipoprotein-levels-insulin-resistance-influence-obstructive-sleep-apnea/…

3D Facial Photography as a Screener for Sleep Apnea 0

3D Facial Photography as a Screener for Sleep Apnea

Three-dimensional facial photography can provide a simple and highly accurate method of predicting the presence of obstructive sleep apnea, according to a study led by The University of Western Australia (UWA).

The research, published in the Journal of Clinical Sleep Medicine, builds on previous work identifying that the structure of the face, head, and neck played a key role in diagnosing sleep apnea.

Professor Peter Eastwood, director of the Centre for Sleep Science, and his research team ran overnight sleep studies while Syed Zulqarnain Gilani, PhD, from UWA’s School of Computer Science and Software Engineering, analyzed the 3D faces.

“What we found was that we could predict the presence of obstructive sleep apnea with 91% accuracy when craniofacial measurements from 3D photography were combined into a single predictive algorithm,” Gilani says in a release.

The study recruited 400 middle-aged men and women who took part in sleep studies at UWA’s Centre for Sleep Science and Sir Charles Gairdner Hospital while their faces were analyzed from 3D photographs. Participants were also recruited from Western Australia’s Raine Study.

The study suggests

Glidewell Dental Oasys Hinge Appliance (PDAC Approved) 0

Glidewell Dental Oasys Hinge Appliance (PDAC Approved)

Glidewell Dental has released a new mandibular advancement device, the Oasys Hinge Appliance. This oral sleep appliance is Medicare and PDAC (Pricing, Data Analysis and Coding) cleared under code E0486 to treat patients with mild to moderate obstructive sleep apnea (OSA).

“Snoring is a warning sign that should not be ignored,” says Randy Clare, director of brand and product management at Glidewell Dental, in a release. “An estimated 50% of US adults snore and 30 percent of people are habitual snorers. In addition, adults over the age of 65 are at an increased risk of obstructive sleep apnea, which can be very serious if left untreated. Two common symptoms of OSA include loud, chronic snoring and daytime sleepiness.”

The Oasys Hinge Appliance is designed to gently shift the lower jaw forward during sleep, which activates the airway muscles and ligaments to prevent the airway from collapsing. The device is custom-made for each patient. It’s micro-adjustable (0.25 mm increments), with up to 10 mm of advancement based on the patient’s needs. The telescope-style hinge allows for natural jaw movement and can

Karl Doghramji, MD: Defining Insomnia 0

Karl Doghramji, MD: Defining Insomnia

In an interview with MD Magazine, Karl Doghramji, MD, a professor at Thomas Jefferson University, explained the technical definition of insomnia, and how that definition has helped shape the clinical understanding of its comorbidities.

And finally, what’s interesting about the new nosologic classification of insomnia is that we no longer look at insomnia being a primary or secondary phenomenon. We now look at as being a problem or disorder which coexists with other disorders, or is comorbid with other disorders. So we’re used to saying insomnia occurred because of this problem, because of that problem. Now, we say in some it’s comorbid with depression, or gastroesophageal reflux, or with sleep apnea.

from Sleep Review http://www.sleepreviewmag.com/2019/08/karl-doghramji-md-defining-insomnia/…

More Cancer Cases Seen Among Women with Sleep Apnea Than in Men and in People Without OSA 0

More Cancer Cases Seen Among Women with Sleep Apnea Than in Men and in People Without OSA

Women with severe sleep apnea appear to be at an elevated risk of getting cancer, a study shows. No causal relationship is demonstrated, but the link between nocturnal hypoxia in women and higher cancer risk is still clear.

“It’s reasonable to assume that sleep apnea is a risk factor for cancer, or that both conditions have common risk factors, such as overweight. On the other hand, it is less likely that cancer leads to sleep apnea,” says Ludger Grote, adjunct professor and chief physician in sleep medicine, and the last author of the current study, in a release.

The research, published in the European Respiratory Journal, is based on analyses of registry data, collected in the European database ESADA, on a total of some 20,000 adult patients with obstructive sleep apnea (OSA). About 2% of them also had a cancer diagnosis.

As expected, advanced age was associated with elevated cancer risk, but adjusting the data for age, gender, body mass index (BMI), smoking, and alcohol consumption nevertheless showed a possible link between intermittent hypoxia at night and higher cancer

The Life of a Person Who Wakes Up Really, Really Early 0

The Life of a Person Who Wakes Up Really, Really Early

“Extreme larks” get up naturally when some people have hardly gone to bed, reports The Atlantic.

There are some limits to this study. Since Ptáček and Jones ran their study at a sleep clinic, most of the patients had sleep apnea. Ptáček said he found that the presence or absence of sleep apnea does not affect whether someone will be a lark or a night owl, but Abbott and other experts I asked were not so sure that the data are perfectly generalizable to the general population.

from Sleep Review http://www.sleepreviewmag.com/2019/08/the-life-of-a-person-who-wakes-up-really-really-early/…

Inspire Medical Systems Launches New Brand Identity and Website 0

Inspire Medical Systems Launches New Brand Identity and Website

Inspire Medical Systems Inc, a medical technology company focused on the development and commercialization of innovative and minimally invasive solutions for patients with obstructive sleep apnea (OSA), recently revealed its new brand identity and launched a new website.

“While our name and focus on patient outcomes remain the same, our brand identity and website, InspireSleep.com, have evolved to ensure prospective patients can easily learn about our innovative sleep apnea treatment,” says Tim Herbert, president and CEO of Inspire Medical Systems, in a release. “Our updated website improves patient education by encouraging website visitors to learn more about Inspire therapy and connect with an Inspire trained medical professional.”

Martin Abrams, vice president of marketing and customer experience, says, “Our focus is on building meaningful and emotional connections. When people struggling with CPAP visit our website, they will find answers to their questions and be able to connect with a medical professional to learn more about our innovative treatment option.”

A new advertising campaign called, “A Button,” also launched in conjunction with the new website. This campaign, which will feature TV,

VirtuOx Seeks to Acquire Substantially All Assets of NovaSom 0

VirtuOx Seeks to Acquire Substantially All Assets of NovaSom

On Aug 2, 2019, NovaSom Inc sought relief from its creditors under Chapter 11 of the Bankruptcy Code in the United States Bankruptcy Court for the District of Delaware. NovaSom is a provider of home sleep apnea testing, utilizing its AccuSom home sleep test.

On that same date, NovaSom filed with the Bankruptcy Court various pleadings, including a motion to sell substantially all of the assets of NovaSom to VirtuOx Inc, subject to higher and better bids, under a court-supervised process designed to, among other things, maintain the operations of NovaSom and transfer them to an approved purchaser, free and clear of all liens, claims, and encumbrances.

At a hearing on Aug 8, the Bankruptcy Court entered numerous orders authorizing NovaSom to continue its operations, fund its payroll and other working capital needs, and thereby preserve and maintain its business, customer relationships, and goodwill, with an anticipated sale date by September 27, 2019.

If VirtuOx is selected as the highest and best bidder and its purchase contract is approved by the Bankruptcy Court, it is the intention of VirtuOx to

How to Get Sleep Apnea Patients into Well-Fitting Interfaces… Remotely 0

How to Get Sleep Apnea Patients into Well-Fitting Interfaces… Remotely

As fewer patients come into sleep labs for mask fittings and titration studies, telemedicine experts and manufacturers share 6 tips for selecting the correct PAP mask the first time.

When people who suspect they have a sleep disorder live far from the nearest sleep medicine clinic, they may turn to telemedicine providers. These days, even patients who do an in-person initial visit may have subsequent visits handled remotely—such as a diagnosis via home sleep test, followed by auto-CPAP titration. But how do you ensure patients are matched properly to their PAP interfaces, when you don’t have the luxury of an in-person fitting?

There are a growing number of options to make sure that remote patients get an interface that fits, on the first try.

1. Look to CPAP Mask Starter Packs

Several CPAP suppliers have mask starter packs available, which often come with three to four cushion sizes. These packs enable patients to try each cushion size, without ever having to coming into an office, to find the one that works the best for them.

“The starter

Type 2 Diabetes Link to Sleep Problems Confirmed in Midlife Women 0

Type 2 Diabetes Link to Sleep Problems Confirmed in Midlife Women

Hormone changes are known to alter insulin sensitivity and glucose metabolism, as well as interfere with women’s sleep patterns. But little was known about the association between diabetes and sleep disturbances during the menopause transition until now, as a new study concludes that women with diabetes are at greater risk for sleep disturbances. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS).

Estrogen and progesterone are known to influence cell response to insulin. As a result, it has been suspected that the hormone changes of the menopause transition could cause fluctuations in a woman’s blood sugar levels, putting her at greater risk of diabetes. Statistically, midlife women have a higher prevalence rate of type 2 diabetes during the menopause transition.

Similarly, hormone changes have been shown to affect a woman’s quality of sleep. Mainly because of night sweats and hot flashes caused by hormone changes, about 42% of premenopausal and 60% of postmenopausal women reportedly have sleep disturbances. For those with diabetes, sleep difficulties could be worsened by various diabetes symptoms and